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Pictured above (from left to right): Ashlyn McGuire, David Alvarado, Nikolette McCombs, Leiah Carey, Dr. Leanna Robbins, Kevin Stoll, Prof. Reza Ghiladi.

Porphyrins and related tetrapyrrole macrocycles play a number of important roles spanning biology, medicine, molecular electronics, and organic geochemistry. These include their use as prosthetic cofactors in proteins such as hemoglobin and the cytochrome P450s, as the basis for the chlorophyll pigments in phototsystems I and II, and as photosensitizers for anticancer photodynamic therapy, to name a few. In the Ghiladi lab, we are interested in both i) the fundamental properties of porphyrins that enable biocatalytic transformations in multifunctional heme enzymes, and ii) their applications as the basis for potent, photoactive antimicrobial materials.

Recent News

March 2017: Wishing Dr. Leanna Robbins a great start to her new job at Syngeta!

February 2017: Ashlyn McGuire is spending 5 weeks working with Dr. Pat Hutchings at the Australian Museum in Sydney.

January 2017: Congratulations to Leiah on being awarded a Dissertation Completion Grant for Spring '17.

December 2017: Our antimicrobial work is featured on WNCN, the CBS affiliate in Raleigh: http://wncn.com/2016/12/06/nc-state-researchers-work-to-kill-antibiotic-resistant-germs/

September 2016: Welcoming the two newest members of the group, David Alvarado and Kevin Stoll.

September 2016: PIs Ghiladi, Argyropoulos and Scholle are awarded an NCBC Biotechnology Innovation Grant to support their work on antimicrobial materials.

July 2016: : PIs Ghiladi, Argyropoulos and Scholle receive funding from the Chancellor's Innvovation Fund for creating the next generation of antimicrobial coatings and paints (https://www.csc.ncsu.edu/news/1921).