Drosophila melanogaster Singh Lab Drosophila melanogaster
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Publications

Singh. N. D., E. A. Stone, C. F. Aquadro and A. G. Clark. Fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the D. melanogaster X chromosome. Genetics 194(2):375-387.

Singh, N. D., J. D. Jensen, A. G. Clark and C. F. Aquadro. 2013. Inferences of demography and selection in an African population of D. melanogaster. Genetics 193:215-228.

Singh, N. D. 2012. Classical genetics meets next-generation sequencing: Uncovering a genome-wide recombination map in Drosophila melanogaster. PLoS Genetics 8(10):e1003024.

Singh, N. D. and K. L. Shaw. 2012. On the scent of pleiotropy. Proceedings of the National Academy of Sciences 109(1):5-6.

Connallon, T., N. D. Singh, and A. G. Clark. 2012. Impact of genetic architecture on the relative rates of X versus autosomal adaptive substitution. Molecular Biology and Evolution 29:1933-1942.

Fiston-Lavier, A. S., N. D. Singh, M. Lipatov and D. Petrov. 2010. Drosophila melanogaster recombination rate calculator. Gene 463:18-20.

Singh, N. D., A. M. Larracuente, T. B. Sackton and A. G. Clark. 2009. Comparative genomics on the Drosophila phylogenetic tree. Annual Review of Ecology, Evolution, and Systematics. 40(10):459-480.

Nishant, K. T., N. D. Singh, and E. Alani. 2009. Genomic mutation rates: What high through-put methods can tell us. Bioessays 31(9):912-920.

Bauer DuMont, V. L., N. D. Singh, M. H. Wright, and C. F. Aquadro. 2009. Locus-specific decoupling of base composition evolution at synonymous sites and introns along the Drosophila melanogaster and Drosophila sechellia lineages. Genome Biology and Evolution 2009:67-74.

Singh, N. D., C. F. Aquadro, and A. G. Clark. 2009. Estimation of fine-scale recombination intensity variation in the white-echinus region of D. melanogaster. Journal of Molecular Evolution 69(1):42-53.

Singh, N.D., P. F. Arndt, A. G. Clark and C. F. Aquadro. 2009. Strong evidence for lineage- and sequence-specificity of substitution rates and patterns in Drosophila. Molecular Biology and Evolution 26(7):1591-1605.

Singh, N. D., A. M. Larracuente and A. G. Clark. 2008. Contrasting the efficacy of selection on the X and autosomes in Drosophila. Molecular Biology and Evolution 25(2):454-467.

Larracuente, A. M., T. B. Sackton, A. Greenberg, A. Wong, N. D. Singh, D. Sturgill, Y. Zhang, B. Oliver and A. G. Clark. Protein-coding gene evolution in Drosophila. 2007. Trends in Genetics 24(3):114-123.

Singh, N. D., V. L. Bauer DuMont, M. J. Hubisz, R. Nielsen, and C. F. Aquadro. Patterns of mutation and selection at synonymous sites in Drosophila. 2007. Molecular Biology and Evolution 24(12):2687-2697.

Drosophila 12 Genomes Consortium. 2007. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450(8):203-218.

Singh, N. D., J. M. Macpherson, J. D. Jensen, and D. A. Petrov. 2007. Similar levels of X-linked and autosomal nucleotide polymorphism in African and non-African strains of Drosophila melanogaster. BMC Evolutionary Biology 7:202.

Singh, N. D. and D. A. Petrov. 2007. Evolution of gene function on the X chromosome and the autosomes in Jean-Nicolas Volff, ed. Genome Dynamics volume 3: Gene and Protein Evolution. Karger, Wurzburg, Germany.

Singh, N. D., P. F. Arndt, and D. A. Petrov. 2006. Minor shift in background substitutional patterns in the Drosophila saltans and willistoni lineages is insufficient to explain GC content of coding sequences. BMC Biology 4:37.

Singh, N. D., J. C. Davis, and D. A. Petrov. 2005. X-linked genes evolve higher codon bias in Drosophila and Caenorhabditis. Genetics 171:145-155.

Singh, N. D., J. C. Davis, and D. A. Petrov. 2005. Codon bias and noncoding GC content correlate negatively with recombination rate on the Drosophila X chromosome. Journal of Molecular Evolution 61:315-324.

Singh, N. D., P. F. Arndt, and D. A. Petrov. 2005. Genomic heterogeneity of background substitutional patterns in Drosophila melanogaster. Genetics 169:709-722.

Singh, N. D., and D. A. Petrov. 2004. Rapid sequence turnover at an intergenic locus in Drosophila. Molecular Biology and Evolution 21:670-680.

Seielstad, M., N. Yuldasheva, N. Singh, P. Underhill, P. Oefner, P. Shen, and R. S. Wells. 2003. A Novel Y-chromosome variant puts an upper limit on the timing of first entry into the Americas. American Journal of Human Genetics 73:700-705.

Srikummool, M., D. Kangwanpong, N. Singh, and M. Seielstad. 2001. Y-chromosomal variation in uxorilocal and patrilocal populations in Thailand in L. Jin, M. Seielstad, and C. Xiao, eds. Genetic, Linguistic, and Archeological Perspectives on Human Diversity in Southeast Asia. World Scientific Publishing, River Edge, New Jersey.