Who We Are

The Sombers Lab is an interdisciplinary group comprising researchers from Chemistry, Biochemistry, Engineering, Biology and Physics. Our research focuses on the development, characterization, optimization, and application of analytical techniques to study neurochemical changes in living brain tissue. Our ability to make complex biological measurements in behaving animals distinguishes us from most analytical chemists by allowing us to use our developments to make significant advances in the field of Neuroscience.  Read More >>

The Sombers Lab is affiliated with the Department of Biomedical Engineering and with the W.M. Keck Center for Behavioral Biology at NCSU.

You can also find us on Facebook.


Recent Happenings

Spring 2014

  • Lars Dunaway has won a very prestigious NSF Graduate Research Fellowship for his work entitled 'Real-Time electrochemical monitoring of opioid peptide dynamics at mammalian cells and in live brain tissue.'
  • It's not quantitative neuroscience, but the Sombers Lab needs to give a big shout out to Scott Sombers, for winning first place at US Nationals in men's alpine snowboarding. Rock on, Scotty Potty!
  • Nastassja Rhodes has been named an IMSD Research Scholar, complete with research assistantship.
  • Welcome to the Sombers Lab, Nastassja Rhodes!
  • Lars Dunaway's poster on monitoring met-enkephalin dynamics in live tissue has won an NCSU Chemistry Outstanding Graduate Research Award
  • Andy Schmidt's poster on carbon nanotube yarns has won the BASF Innovation Graduate Research Award, as well as the best overall poster at the NCSU Graduate Research Symposium. Strong work, Andy!
  • James Roberts paper on in situ, real-time electrode calibration was published in Analytical Chemistry
  • The Sombers lab participated in Brain Awareness Week events at the NC Museum of Life and Science in Durham, as well as at the NC Museum of Natural Sciences in Raleigh
  • Dr Sombers participated in the Brains and Behavior Distinguished Lecture Series at Georgia State University.
  • We are happy to welcome our new technician, Christie Lee.
  • Dr Sombers killed it in the Winter Brain snowboard race at Steamboat,winning first place!
  • Fall 2013

    • Leyda Lugo-Morales was hired as a forensic scientist by the NC State Bureau of Investigation - Congratulations, Leyda!
    • Andy Schmidt's nanotube yarn electrodes are featured in a nanotechnology spootlight on nanowerk.com

    Summer 2013

    • Leyda Lugo-Morales's glucose paper was accepted to Analytical Chemistry
    • Andy Schmidt's first paper was accepted to ACS Nano
    • Lingjiao and Leslie are working with Lee County teachers in two Chemistry workshops in July
    • Congratulations to Doctora Leyda for defending her PhD in Chemistry!
    • Leslie, Lingjiao Qi, and Elina Thomas are working once again with Carol Chappell and Lee County elementary and middle school teachers to help build a strong foundation in Chemistry for our NC kids.
    • The Sombers Lab Outreach Video, created for 8th graders at Lee County Schools, directed and produced by Julie Gras-Najjar, is fricking SWEET!
    • We are happy to welcome incoming graduate students Nathalia Ortiz and Samantha Smith, as well as a new Research Asst Prof, Tiger Xie this summer.

    Spring 2013

    • Congratulations to Steph Hughes for her master's degree in Chemistry and a great new job in the triangle at bioMerieux Inc.
    • Leyda Lugo-Morales, was awarded the SIGMA XI Chapter Research Award in recognition of superior achievements in academic research.
    • Marina's paper was just accepted at ACS Chemical Neuroscience.
    • Steph Hughes has won an NSF Graduate Research Fellowship! Way to go, Steph!
    • Leyda's voltammetric glucose sensor work was featured in SCOPE magazine.
    • Leyda's voltammetric glucose sensor work was featured in the Technician.
    • Congratulations to James Roberts, the first PhD from the Sombers Lab!
    • Leyda Lugo-Morales has won first place in the 8th Annual Graduate Student Research Symposium with her poster presentation entitled "Enzyme-modified Carbon Fiber Microelectrode Based on the Voltammetric Detection of H2O2". The Symposium was held, Tuesday, March 19. More information is posted at the Symposium web page.
    • Dr Sombers, Lingjiao Qi and Andy Schmidt presented their work at PittCon 2013 in Philadelphia, March 17-21.
    • Congrats to Steph Hughes! She has lined up a job for after her defense this spring. She will be an Inorganic Environmental Chemist at First Analytical in Raleigh.
    • The Sombers lab participated in the “Building the Brain” interactive exhibit at the NC Museum of Life and Science for Brain Awareness Week, Durham NC, March 2013.
    • The Sombers lab has been BUSY with some outreach! We developed and taught exciting chemistry activities to eighth grade students at East Lee Middle School in Sanford, NC. Prior to this event, we sent a SWEET introductory video and held a video chat discussion with each of the six classes to prepare them for our visit.
    • Dr. Sombers was elected to the Society of Electroanalytical Chemistry Board of Directors.
    • New publication! Roberts, J.G., Lugo-Morales, L.Z., Loziuk, P.L.*, and Sombers, L.A. Real-time Chemical Measurements of Dopamine Release in the Brain, Methods Mol Biol. 2013; 964:275-94.
    • Dr Sombers gave a lecture at the Winter Brain Conference in January, and won first place in the Smitty Stevens race - on a snowboard!
    • Filming begins for the Sombers lab outreach video.

    Copyright © 2010 Leslie Sombers. Site design by Ruben Moreno. All rights reserved.