Department of Biology, North Carolina State University

Heather B. Patisaul

The Patisaul Lab

I examine the steroid-dependent mechanisms through which sexually dimorphic behaviors and brain circuits arise. I also explore the mechanisms by which sexually dimorphic systems and behaviors can be disrupted by environmental estrogens.  We are particularly interested in the mechanisms by which exposure to environmental estrogens can advance puberty and impair fertility in females.  To achieve this, our lab uses an integrative approach combining behavioral biology, neuroanatomy neuroendocrinology and molecular biology. 

It is our hope that this complementary research strategy, will ultimately yield information that will help determine if exposure to endocrine disrupting compounds pose a health risk to humans, particularly pregnant women and children.

To address these questions we employ a variety of techniques including in situ hybridization, autoradiography, immunohistochemistry, stereology, confocal microscopy, animal behavior assays, and high throughput technology.

 

To contact us:

Department of Biology

North Carolina State University

127 David Clark Labs

Raleigh, NC 27695

(919) 513-7567

Heather_Patisaul@ncsu.edu