GIBSON Drosophila Quantitative Genetics Lab

Department of Genetics, North Carolina State University

3606 Gardner Hall, Raleigh NC 27695-7614

(919) 513-2512

ggibson@unity.ncsu.edu

 

We are taking a Reverse Quantiative Genetic approach to understanding the molecular basis of morphological and behavioral genetic variation, using the fruitfly Drosophila melanogaster as a model organism.

One arm of the lab works on the evolution of wing shape, studying the role of polymorphism in the EGF-Ras pathway in the production of shape variation.

The other arm has begun work on heart rate and drug susceptibility as candidate traits that are likely to be affected by variation in dopamine and serotonin activity.

In the course of these studies, we are assembling a single nucleotide polymorphism SNP database of the Drosophila genome. Many of the differences between the Celera sequence and existing GenBank entries documented here may also represent true SNP polymorphisms, although we have not confirmed this in most cases.

 

Please visit "Flyvolution", a list of Labs working on Evolution and Development in Drosophila, including links to graduate department and personal home pages.

 

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Genome Research Lab

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