Research

 

Research Interests

I am interested in using mathematics to study biological phenomena. I am particularly interested in mathematical modeling of cellular and molecular physiology. In doing so, I utilize a combination of deterministic and stochasitc methods, as well as a healthy amount of computational support for model simulation. Here is a list of current research topics:

  • metabolic regulation and type 2 diabetes
  • reactive oxygen species (ROS) and insulin resistance (IR)
  • the unfolded protein response (UPR) and beta-cell dysfunction
  • female hormone regulation and polycystic ovary syndrome (PCOS)
  • blood clotting and anticoagulation therapy

Publication

E.J. Graham and F.R. Adler. Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression. Journal of theoretical biology 340 (2014): 238-250.

CONTACT INFORMATION
Office: SAS 3266
Phone: 919.515.0682
E-mail: ejgraha2@ncsu.edu

North Carolina State University
Department of Mathematics
Raleigh, NC 27695