Center for Integrated Fungal Research

North Carolina State UniversityCollege of Agriculture and Life Sciences
home page for Doug Brown

 
two approaches to analysis
Doug Brown
Fungal Genomics Laboratory
North Carolina State University
Campus Box 7251
Raleigh, NC 27695-7251
debrown@unity.ncsu.edu
Tel: (919) 513-0394
Fax (919) 513-0024

(yes, I'm the guy with the hat, which one depends upon the
day)

 

Curriculum Vitae

  Current research highlights include:
Analysis of cross-species orthologous kinase interactions experimentally determined by CHiP-chip processes.

Analysis and interpretation of small RNA components of the plant pathogenic fungus Magnaporthe oryzae.

Whole genome sequence project for the plant and human pathogenic fungus Aspergillus flavus.

Whole genome sequence project for plant pathogenic fungus Rhizoctonia solani.
Past research highlights include:
Whole genome sequence project for the plant pathogenic fungus Magnaporthe grisea (now called Magnaporthe oryzae).

High throughput computing systems for bioinformatic analysis.

Security and trust determination in distributed grid based workflow and collaborative computational systems.

Computational systems for the model plant genome Trunculata medicago whole genome sequence project.

Analysis as part of the plant pathogenic rust fungus Puccinia graminis.

Analysis as part of the major industrial fungus Trichoderma reesei.

  My desired research objective is to build cellular models for in-silico experimentation. The blue sky goal is to treat those models as non-linear dynamic systems where-in I can create Iterated Function Systems to explore the relationship between self structuring at the boundaries of chaotic transitions and cellular functioning.  To that end, I am spending a lot of time laying, laying, and more laying of bricks on Bioinformatics foundations and providing computational support for biologists.

  I am moderately new to the world of applied Bioinformatics. Most of my experience comes from 25 years in the computer industry. I have, however, been tracking the computational biology world since 1990.  I am also the lead of the center's Bioinformatics support group.