Deiters Lab
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NC State University
The Deiters Lab of Chemical Biology
We are sharing reagents, chemicals, and constructs developed in our lab with researchers all over the world. If you would like to request materials for your research, please send us an email. Some materials require a simple Materials Transfer Agreement (MTA) between your institution and NCSU. Please take a look at the list below which includes structures, brief descriptions, and selected references.
Caged erythromycin for light-activation of gene function in bacterial cells. [76]
Caged thymidine phosphoramidite for the light-regulation of oligonucleotide function, especially antisense function. [61] [44] [43] [40] [29] [26]
Caged deoxyguanosine phosphor-amidite for the light-regulation of oligonucleotide function. [33]
photochemical genetics
photochemical genetics
Caged oligonucleotides. Please feel free to discuss the synthesis of light-activated oligonucleotides with us. [61] [44] [43] [40] [29]
Caged thymidine morpholino monomer for the light-regulation of antisense function. [67]
Caged thymidine phosphoramidite for the light-regulation of oligonucleotide function with two-photon excitation. [56]
Caged IPTG for light-activation of gene function in bacterial cells. [24]
Caged rapamycin for light-activation of kinase function in mammalian cells. [70]
Caged toyocamycin for light-activation of gene function in mammalian cells. [42]
photochemical genetics
Caged tyrosine for the light-activation of protein function. [74] [58] [57] [49] [46]
Caged lysine for the light-activation of protein function. [71] [66] [60]
Alkyne-modified lysine for protein bioconjugation. [48]
Azide-modified lysine for protein bioconjugation. [48]
Lysine photocrosslinker for protein-protein interaction studies. [68]
photochemical genetics
MicoRNA miR-21 inhibitor. [36]
MicoRNA miR-122 inhibitor. [62]
MicoRNA miR-122 inhibitor. [62]
TGF-beta pathway inhibitor. [72]
Caged theophylline for light-activation of ribozyme function. [19]
Plasmid encoding photocaged Cre recombinase. [46]
Plasmid encoding photocaged Taq polymerase. [49]
Plasmid encoding photocaged T7 RNA polymerase. [58]
Plasmid encoding photocaged zinc-finger nuclease. [74]
Plasmid encoding miR-122 luciferase reporter. [62]