|
|
Introduction
to Applied Bioprocessing |
||
|
Course # |
BEC(MB)180 |
||
|
Instructor |
Dr. José Manuel Bruno-Bárcena 1552A Gardner Hall Addition North Carolina State University Raleigh, NC
27695 |
Phone:
919-513-1495 |
|
|
|
Dr. Driss Elhanafi |
Phone:
919-513-8236 email: delhana@gw.fis.ncsu.edu |
|
|
|
M.S.
Matthew Evans |
Phone:
919-513-8094 email: mrevans@ncsu.edu |
|
|
|
M.S.
Haiwei Zhang |
Phone: 919-513-1699
email: hzhang6@gw.fis.ncsu.edu |
|
|
|
850 Oval Drive,
Suite 195 Raleigh, NC 27695-7928 |
|
|
|
Prerequisites |
High
school Biology and Chemistry |
||
|
Class Hours Office Hours |
Lecture
- Laboratory–
Friday, July 09 – August 3, from 9 am to 3:30 pm Tuesday,
1500-1530 Monday |
||
|
Credit Hours |
2 |
||
|
Restrictions |
Who should apply?
|
||
|
Course Website |
|||
|
Delivery Format |
This
is a Summer class. Students are required to attend daily lectures and laboratories
during the weeks the course is taught. |
||
|
Course Description |
The course
introduces students to basic biomanufacturing tools and experiences, coupled
with data analysis, interpretation, and presentation. The course provides a hands-on learning experience
that challenges students to enhance existing skills, learn new information,
and apply learning to understand biomanufacturing fundamentals. The educational environment will emphasize
team-based decisions, collaborations and consideration of multiple
perspectives. The course culminates
with students cloning and growing cells, expressing, clarifying, purifying,
formulating and packaging vials of a recombinant protein. Students
successfully completing this experience will understand the fundamentals of
biomanufacturing, empowering them to intelligently evaluate biotechnology
career options. Through
this course, students will apply skills and perform operations that are
relevant to the biomanufacturing industries.
Transportation will be provided for field trips to local
biomanufacturing facilities. |
||
|
Technology Requirements |
In
order to complete the course, all students will be required to have access to
an active internet connection. If you
do not have Adobe Acrobat Reader installed on your computer, you will need to
go to the following web site and follow the instructions to download a free
version. |
||
|
Text Requirements |
All required reading material is
contained within the course or is available through a World Wide Web link
provided within the course content. At
present, all laboratory reading materials will be provided. The class links page
is also available as a source of the following references for the module: 1. Shuler, M.L., Kargi, F., editors
2002. Bioprocess Engineering: Basic Concepts. Prentice-Hall of India
(ISBN0130819085) $127.00 2. Harley-Prescott 2002. Laboratory Exercises
in Microbiology, Fifth Edition. The McGraw-Hill Companies. (ISBN0072333456)
$70.63 These references will also be
available in the Reserve Room of the D. H. Hill Library. |
||
|
Learning Outcomes |
At the end of
this course, you should be able to:
|
||
|
Lecture & Laboratory Outlines by
Topical Areas |
Week 1 Read
Chapter 2, An Overview of Biological Basics, Section 2.1 (pp. 11-25), and
Sections 2.3-2.4 (pp. 46-54) Prior
to the Unit 1 Lab, review the section of your lab manual entitled ORIENTATION
TO THE LABORATORY: RULES OF CONDUCT AND GENERAL SAFETY. Monday
Tuesday
Wednesday Read
Exercise 13 Lab Manual
Thursday Read
Exercise 19 Lab Manual
Friday
Week 2 Monday
Tuesday Read Exercise 1 Lab Manual
Wednesday
Thursday
Friday Read
the following: Chapter
4, How Cells Work, Sections 4.1 – 4.5 (pp. 105-119)
|
Week 3 Chapter
6, How Cells Grow, read the following: Sections
6.1 - 6.2.2 (pp. 155-168) Monday Read
Exercise 45 Lab Manual
Tuesday Read
Biotechnology Explorer™ pGLO™ Bacterial Transformation Kit
Wednesday Read
Chapter 8, How Cellular Information Is Altered, Sections 8.1 – 8.6 (pp.
219-241)
Thursday
Friday Read
Biotechnology Explorer™ pGLO™ Bacterial Transformation Kit
Week 4 Monday
Tuesday
Wednesday
Thursday
Friday |